产品货号：
Z31433
中文名称：
EIF2AK4抗体
英文名称：
Anti-EIF2AK4 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-EIF2AK4 Antibody |
| 指标别名 | Eukaryotic translation initiation factor 2 alpha kinase 4;GCN2;PVOD2;EIF2AK4 |
| 克隆性 | Monoclonal |
| 检验物种 | human |
| 应用范围 | WB,IHC,ICC/IF,FCM |
| 基因名称 | EIF2AK4 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | A synthesized peptide derived from human GCN2. |
| 实际分子量 | 180～200KD |
| 成分 | 500μg/mL;Rabbit IgG in phosphate buffered saline,pH7.4,150mM NaCl,0.02% sodium azide and 50% glycerol. |
| 纯化方式 | Affinity-chromatography |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | EIF2AK4(Eukaryotic Translation Initiation Factor 2-Alpha Kinase 4),also called GCN2,is an enzyme that in humans is encoded by the EIF2AK4 gene.EIF2AK4 belongs to a family of kinases that phosphorylate the alpha subunit of eukaryotic translation initiation factor-2 to downregulate protein synthesis in response to varied cellular stresses.Hartz(2005) mapped the EIF2AK4 gene to chromosome 15q15.1 based on an alignment of the EIF2AK4 sequence with the genomic sequence.Berlanga et al.(1999) demonstrated that Gcn2 immunopurified from mouse liver extracts could phosphorylate rabbit Eif2 in vitro.Serum starvation increased the level of phosphorylated EIF2-alpha more than 2-fold in human embryonic kidney cells transfected with mouse Eif2ak4.Costa-Mattioli et al.(2005) reported a unique feature of hippocampal slices from Gcn2-null mice:in CA1,a single 100-Hz train induced a strong and sustained long-term potentiation(late LTP or L-LTP),which was dependent on transcription and translation. |
| Uniprot ID | Q9P2K8 |
| 推荐稀释比 | Western blot (WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:20～100ICC/IF 1:50～1:200 FC 1:50 |
相关搜索：EIF2AK4抗体，EIF2AK4单抗，Anti-EIF2AK4 Antibody